Ruud van Nistelrooy will take over on an interim basis.
Manchester United clinched a sixth consecutive Premier League win for the first time since April 2015 as Juan Mata and Zlatan Ibrahimovic scored second-half goals in a controversial 2-0 victory at 10-man West Ham United on Monday.
Manchester United closed in on the Premier League's pole position after a 2-1 home win over Aston Villa on Friday put them level on points and games played with champions and leaders Liverpool.
A brilliantly-worked goal by Ryan Christie and a Justin Kluivert penalty gave Bournemouth shock 2-0 Premier League win at home to 10-man Arsenal.
Wayne Rooney scored twice, the first an astonishing 58-metre volleyed contender for Goal of the Season, as Manchester United won their second game in four days by brushing aside West Ham United 2-0 at Upton Park on Saturday.
Manchester City took another decisive step toward an unprecedented fourth successive Premier League title with a 4-0 demolition of Fulham.
Jarrod Bowen and Mohammed Kudus' second-half goals gave West Ham a 2-0 win over Manchester United in the Premier League's early game on Saturday, as the Hammers briefly moved into the top six.
Nearly two decades later, Aditi Chauhan retires as a trailblazer, having become the first Indian woman to play professional football in Europe.
West Ham United could face repercussions after several pitch invasions and ugly scenes in the stands during the second half of a crushing 3-0 home Premier League defeat by Burnley on Saturday.
A summary of Sunday's action in the Premier League.
Tottenham Hotspur and Newcastle United both sealed comeback victories to boost their European qualification hopes.
IMAGES from the Premier League matches played on Tuesday.
Manchester United's current malaise was laid bare as they struggled past third-tier Rochdale 5-3 on penalties after a 1-1 draw in the League Cup third round.
Brown Ideye scored twice as West Bromwich Albion progressed to the quarter-finals of the FA Cup.
Premier League leaders Arsenal needed two own goals, the second deep in stoppage time, to scrape a 2-1 home win over bottom club Wolverhampton Wanderers and open a five-point gap, while earlier on Saturday Mohamed Salah put aside a tumultuous week to help Liverpool beat Brighton and Hove Albion 2-0.
Arsenal snapped a season-long jinx against Newcastle United with a nervy 1-0 win in their last Premier League home game on Sunday.
IMAGES from the UEFA Champions League matches played on Tuesday
Tottenham Hotspur hammered 10-man Aston Villa 4-0 in the Premier League on Sunday thanks to four second-half goals, allowing them to close the gap with their Birmingham rivals to two points in the chase for Champions League football next season.
Louis van Gaal praised his side's attacking display against West Ham United but said they 'forgot to score goals' after a fourth 0-0 draw in their last six home matches on Saturday.
Arsenal reclaim provisional top spot with 1-0 win at Man United
Fresh off a dominant title-winning campaign, Liverpool kick off the new Premier League season on Friday as the team to beat, as the Reds have transitioned from Juergen Klopp's high-octane chaos to a more measured possession-based style under Arne Slot.
Images from Sunday's action in the Premier League.
The Premier League's bottom two clubs met at Goodison Park and there was more woe for Everton as they bowed out on penalties to Southampton after a 1-1 draw.
Arsene Wenger's final match at Old Trafford as Arsenal manager ended in defeat with a stoppage time header from substitute Marouane Fellaini earning the points for second-placed Manchester United.
Champions Manchester City struggled in this campaign and sit sixth in the table after winning only two of their last 10 league matches.
West Ham suffer Fabianski injury blow
A summary of Saturday's action in the Premier League.
Dimitri Payet struck a brace for the Hammers against a tired Newcastle, whose players had to trudge the last mile to West Ham United's stadium after their team coach became stuck in London's rush-hour traffic before Monday's Premier League fixture.
Images from Monday's action in the Premier League.
Manchester City roared back to the top of the Premier League with a 6-1 thrashing of Bournemouth after Manchester United steadied the ship
West Ham United's English League Cup game against Aldershot and Charlton Athletic's match with Reading on Tuesday have been postponed due to the riots sweeping London.
Manchester United will travel to third-tier MK Dons in the Capital One Cup second round following the draw on Wednesday, the first time they have been involved at this stage of the competition for 19 years.
Two spectacular goals from England winger Shaun Wright-Phillips kept Chelsea firmly on Manchester United's heels after a 4-1 win over West Ham United at Upton Park on Wednesday.
Former Manchester United and Chelsea manager Dave Sexton has died aged 82, the English Football Association said in a statement on Sunday.
Photos from the English Premier League matches played on Wednesday
Images from Wednesday's action in the English Premier League.
A summary of Sunday's action in the Premier League.
The government last month opened the door for elite sport to resume and the Premier League said it would restart its season on June 17.
"After feeling strange in the second half of the Burton game in September, I underwent a series of tests," he said.
A quick fire Wayne Rooney hat-trick rescued Manchester United on Saturday as they went eight points clear at the top of the Premier League after coming from two goals down to beat West Ham United 4-2.